Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes.

Carl D LangefeldMary E ComeauNeeraj K SharmaDonald W BowdenBarry I FreedmanSwapan Kumar Das

Published in: Obesity (Silver Spring, Md.) (2018)

Adipose and muscle transcripts comprehensively define pathways involved in regulating glucometabolic disorders. Cis-eQTLs for CP-associated genes may act as primary causal determinants of glucometabolic phenotypes by regulating transcription of key genes.

Keyphrases

transcription factor
skeletal muscle
genome wide identification
genome wide
insulin resistance
adipose tissue
bioinformatics analysis
gene expression
genome wide analysis
metabolic syndrome
oxidative stress
heat shock
heat stress