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Anticancer effects of brusatol in nasopharyngeal carcinoma through suppression of the Akt/mTOR signaling pathway.

Songbin GuoJinling ZhangCairong WeiZhiyong LuRulong CaiDanqi PanHanbin ZhangBaoxia LiangZhenfeng Zhang
Published in: Cancer chemotherapy and pharmacology (2020)
These observations indicate that brusatol is a promising antitumor drug candidate or a supplement to current chemotherapeutic therapies to treat NPC.
Keyphrases
  • signaling pathway
  • pi k akt
  • cell proliferation
  • epithelial mesenchymal transition
  • induced apoptosis
  • adverse drug
  • oxidative stress