Liquid chromatography/electrospray ionization tandem mass spectrometry study of repaglinide and its forced degradation products.

C Purna ChanderB RajuM RameshG ShankarRagampeta Srinivas

Published in: Rapid communications in mass spectrometry : RCM (2018)

The forced degradation of RP carried out as per ICH guidelines results in the formation of six degradation products which have been characterized using LC/MS/MS in combination with accurate mass measurements.

Keyphrases

tandem mass spectrometry
liquid chromatography
ultra high performance liquid chromatography
high performance liquid chromatography
mass spectrometry
simultaneous determination
high resolution mass spectrometry
gas chromatography
high resolution
solid phase extraction
clinical practice
ms ms