MicroRNA profile of pediatric pilocytic astrocytomas identifies two tumor-specific signatures when compared to non-neoplastic white matter.
Luiz Guilherme DarrigoRegia Caroline Peixoto LiraPaola Fernanda FedattoDavid Santos Marco AntonioElvis Terci ValeraSimone AguiarJosé Andres YunesSilvia Regina BrandaliseLuciano NederFabiano Pinto SaggioroAline Paixão BeckerRicardo Santos de OliveiraHélio Rubens MachadoRodrigo Alexandre PanepucciLuiz Gonzaga ToneCarlos Alberto ScrideliPublished in: Journal of neuro-oncology (2018)
In summary, our data demonstrate that PA harbors at least two distinct miRNA signatures, including a subgroup of patients with NF1/PA lesions.