Contrasting effect of the latency-reversing agents bryostatin-1 and JQ1 on astrocyte-mediated neuroinflammation and brain neutrophil invasion.
Alizé ProustCorinne BaratMathieu LeboeufJean DrouinMichel J TremblayPublished in: Journal of neuroinflammation (2017)
These observations highlight the need to carefully assess the potential harmful effect to the CNS when selecting LRA for HIV-1 reactivation strategies.
Keyphrases
- antiretroviral therapy
- hiv positive
- cerebral ischemia
- hiv infected
- human immunodeficiency virus
- hiv testing
- hepatitis c virus
- resting state
- traumatic brain injury
- hiv aids
- blood brain barrier
- white matter
- cell migration
- lipopolysaccharide induced
- men who have sex with men
- lps induced
- cognitive impairment
- functional connectivity
- human health
- inflammatory response
- risk assessment
- brain injury