Outcomes following limited-volume proton therapy for multifocal spinal myxopapillary ependymoma.
Wen Shen LooiDaniel J IndelicatoRaymond B Mailhot VegaChristopher G MorrisEric SandlerPhilipp R AldanaJulie A BradleyPublished in: Pediatric blood & cancer (2020)
54 GyRBE to a limited volume appears effective for disseminated spinal MPE in both the primary and salvage settings, sparing children the toxicity of full craniospinal irradiation. Compared with historical reports, this approach using proton therapy improves the therapeutic ratio, resulting in minimal side effects and high rates of disease control.