Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage.
Nour K MajbourJan AaslyIlham AbdiSimona GhanemDaniel ErskineWilma D J Van de BergOmar M A El-AgnafPublished in: Neurology (2022)
This study provides Class III evidence that CSF-seeded αSyn oligomers can accurately discriminate patients with PD and normal controls and CSF-seeded αSyn oligomers levels correlate with PD severity.