Inflammatory-mediated atrial cardiomyopathy diagnosed using multimodality imaging and successfully treated with prednisolone: a case report.
Birgitte Carbuhn LarsenKadhem Helo Abbas Al-BadriSøren MellemkjærSteen BærentzenChristina Stolzenburg OxlundKasper PrydsPublished in: European heart journal. Case reports (2024)
Diabetes mellitus is an important risk factor for developing atrial fibrillation and diabetic cardiomyopathy, due to reduced levels of anti-inflammatory and increased levels of proinflammatory cytokines causing cardiac inflammatory structural remodelling. The regression of the atrial thickening might be due to prednisolone's anti-inflammatory effects and thereby ability to suppress atrial remodelling and reduce the occurrence of atrial fibrillation. However, the effect of prednisolone might only affect the non-manifested inflammatory-mediated atrial remodelling. Due to the rare occurrence of isolated atrial cardiomyopathy a multiple imaging approach during the diagnostic process and follow-ups are essential to determine the aetiology and effect of the treatment.
Keyphrases
- atrial fibrillation
- catheter ablation
- left atrial
- heart failure
- oral anticoagulants
- left atrial appendage
- direct oral anticoagulants
- high resolution
- left ventricular
- oxidative stress
- anti inflammatory
- risk assessment
- percutaneous coronary intervention
- mitral valve
- coronary artery disease
- mass spectrometry
- weight loss
- acute coronary syndrome
- adipose tissue
- glycemic control
- combination therapy
- fluorescence imaging
- wound healing
- skeletal muscle