Cefiderocol-containing regimens for the treatment of carbapenem-resistant A. baumannii ventilator-associated pneumonia: a propensity-weighted cohort study.

Emanuele RandoSalvatore Lucio CutuliFlavio SangiorgiEloisa Sofia TanzarellaFrancesca GiovannenzeGiulia De AngelisRita MurriMassimo AntonelliMassimo FantoniGennaro De Pascale

Published in: JAC-antimicrobial resistance (2023)

Cefiderocol-containing regimens were associated with reduced 28-day mortality in CRAB-VAP. The sample size and the observational design limit the study's conclusions. Future RCTs are needed to establish cefiderocol's definite role in these infections.

Keyphrases

gram negative
multidrug resistant
magnetic resonance
cardiovascular events
computed tomography
cardiovascular disease
coronary artery disease
network analysis
smoking cessation