Interferon ε restricts Zika virus infection in the female reproductive tract.

Chuan XuAnnie WangLaith EbrahamLiam SullivanCarley TaskerVanessa PizutelliJennifer CouretCyril HernandezPratik Q DebLuke FritzkySelvakumar SubbianNan GaoYungtai LoSelvakumar SubbianAmariliz RiveraAlexander LemenzePatricia Fitzgerald-BocarslySanjay TyagiWuyuan LuAimee BeaulieuTheresa L Chang

Published in: bioRxiv : the preprint server for biology (2023)

gene have abnormal epithelial development and tissue architecture in the cervicovaginal tract. The role of IFNε in protecting host against ZIKV is FRT-specific and is independent of IFNAR1 signaling. Our findings suggest potential preventive strategies based on harnessing mucosal immunity against STIs.

Keyphrases

dendritic cells
zika virus
immune response
genome wide
copy number
big data
genome wide identification
ulcerative colitis
deep learning
gene expression
artificial intelligence
climate change