Monoclonal antibodies from a patient with anti-NMDA receptor encephalitis.
Rashmi SharmaFetweh H Al-SaleemJessica PanzerJiwon LeeRama Devudu PuligeddaLiza F FelicoriChandana Devi KattalaAmy J RattelleGregory IppolitoRobert H CoxDavid R LynchScott K DessainPublished in: Annals of clinical and translational neurology (2018)
These mAbs recapitulate features demonstrated in previous studies of ANRE patient CSF, and exert effects on NMDAR in vitro and in vivo consistent with modulation of NMDAR activity.
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