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The first Canadian experience with the Afirma® gene expression classifier test.

Emily Kay-RivestJamie TibboSarah BouhabelMichael TamiliaRebecca LeboeufVeronique-Isabelle ForestMichael P HierLoren SavouryRichard J Payne
Published in: Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale (2017)
Molecular analysis is increasingly used in the management of indeterminate thyroid nodules. This study highlights the experience of two Canadian centres with AGEC testing. We found inter-institutional variability in the rate of nodules returning as "benign," however we found similar rates of confirmed malignancy in nodules returning as "suspicious." According the literature, results for AGEC testing in two Canadian institutions align with results reported in American centres.
Keyphrases
  • gene expression
  • systematic review