Pre-eclampsia and long-term cardiac dysfunction: A review of asymptomatic cardiac changes existing well beyond the post-partum period.
Archana Selvakumar ThayaparanJoanne M SaidSandra A LoweAnthony McLeanYang YangPublished in: Australasian journal of ultrasound in medicine (2019)
Women with a history of early or preterm pre-eclampsia have an increased prevalence of diastolic dysfunction. This review demonstrates that the cardiac dysfunction associated with previous pre-eclampsia is quantifiable and persistent. Progression of heart failure from asymptomatic to symptomatic stages carries a fivefold increase in mortality. The use of echocardiography could detect cardiac dysfunction in the asymptomatic stage and guide more intensive risk factor modification in these women.
Keyphrases
- left ventricular
- heart failure
- risk factors
- oxidative stress
- blood pressure
- cardiac resynchronization therapy
- computed tomography
- polycystic ovary syndrome
- pregnant women
- type diabetes
- pulmonary hypertension
- cardiovascular disease
- skeletal muscle
- adipose tissue
- insulin resistance
- metabolic syndrome
- preterm birth
- coronary artery disease
- preterm infants
- gestational age
- pregnancy outcomes