Toxoplasma gondii infection reduces serum progesterone levels and adverse effects at the maternal-foetal interface.

Carina BritoTânia Magalhães SilvaMaria M CastroWeronika WyrwasBárbara OliveiraBruno M Fonseca Pedro N Oliveira Craig W Roberts Natércia Teixeira Margarida Borges

Published in: Parasite immunology (2019)

Maternal T gondii infection induced adverse effects at the maternal-foetal interface. Alterations were found in immune spleen cells, dependent on the day of pregnancy, relative to nonpregnant animals. The results obtained suggest a pregnancy-dependent mechanism during T gondii infection able to interfere with macrophage numbers.

Keyphrases

pregnancy outcomes
toxoplasma gondii
birth weight
gestational age
preterm birth
induced apoptosis
high glucose
signaling pathway