Genome-wide association study reveals a novel locus for asthma with severe exacerbations in diverse populations.

Esther Herrera-Luis Antonio Espuela-Ortiz Fabian Lorenzo-Diaz Kevin L Keys Angel C Y MakCeleste EngScott HuntsmanJesus VillarJose R Rodriguez-SantanaEsteban González Burchard Maria Pino-Yanes

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)

We identified a novel susceptibility locus for severe asthma exacerbations in Hispanic/Latino and African American youths with functional effects in gene expression and methylation status of neighboring genes.

Keyphrases

african american
genome wide association study
chronic obstructive pulmonary disease
gene expression
dna methylation
genome wide
cystic fibrosis
lung function
early onset
genome wide identification
allergic rhinitis