All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells.

Nikolaos TsotakosImtiaz AhmedTodd M UmsteadYuka ImamuraEric YauPatricia SilveyraZissis C Chroneos

Published in: PloS one (2022)

Our findings support the idea that ATRA supplementation may decrease hyperoxia-induced disruption of the neonatal respiratory epithelium and alleviate development of BPD.

Keyphrases

high glucose
diabetic rats
signaling pathway
drug induced
oxidative stress
immune response
nuclear factor
pi k akt
inflammatory response
toll like receptor