NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy.
Loukovaara SirpaNiina PiippoKati KinnunenMaria HyttiKai KaarnirantaAnu KauppinenPublished in: Acta ophthalmologica (2017)
Our results suggest that NLRP3 inflammasome activation can be associated especially with the pathogenesis of PDR. The lack of differences in TNF-α, IL-6, and IFN-γ also alludes that acute inflammation or T-cell-mediated responses do not dominate in PDR pathogenesis.