Receptor activator of nuclear factor-kappa B is enriched in CD9-positive extracellular vesicles released by osteoclasts.

Shaobo RuanWellington J RodyShivani S PatelLina I HammadiMacey L MartinLorraine P de FariaGeorge DaaboulLeif S AndersonMei HeL Shannon Holliday

Published in: Extracellular vesicles and circulating nucleic acids (2023)

RANK was enriched in a subset of the CD9-positive EVs. The current study provides the first report of selective localization of RANK in subsets of EVs.

Keyphrases

nuclear factor
toll like receptor
inflammatory response
immune response
bone loss
binding protein