Rehydration with fructose worsens dehydration-induced renal damage.

Tamara MilagresFernando E García-ArroyoMiguel A LanaspaGabriela GarciaTakuji IshimotoAna Andres-HernandoMasanari KuwabaraThomas JensenYuka SatoJason GlaserLaura G Sánchez-LozadaRichard Joseph JohnsonCarlos Roncal-Jimenez

Published in: BMC nephrology (2018)

These studies suggest that heat stress may activate intrarenal inflammasomes leading to inflammation and renal injury, and provide evidence that rehydration with fructose may accelerate the renal injury and inflammatory response.

Keyphrases

heat stress
inflammatory response
oxidative stress
diabetic rats
high glucose
lipopolysaccharide induced
immune response
endothelial cells
lps induced