Altered impulsivity across drug-naïve parkinsonism, isolated REM sleep behavior disorder, and their high-risk relatives.

A complex construct of altered impulsivity with decreased risk taking but increased reflection and motor impulsivity has already occurred at the prodromal and early stages of α-synucleinopathy, which have implications for underlying pathophysiology and clinical management of α-synucleinopathy, especially for impulse control behaviors upon dopaminergic drug treatment. This article is protected by copyright. All rights reserved.