Assessment of Neurovascular Uncoupling: APOE Status is a Key Driver of Early Metabolic and Vascular Dysfunction.

Kristen OnosPeter B LinRavi S PandeyScott A PersohnCharles P BurtonEthan W MinerKierra EldridgeKate E FoleyGareth R Howell Paul R Territo

Published in: bioRxiv : the preprint server for biology (2023)

status determines key differences in progression to neurovascular uncoupling. Our method detects changes in neurovascular coupling, and may serve as an early diagnostic biomarker.

Keyphrases

nitric oxide synthase
cognitive decline
high fat diet
room temperature
adipose tissue
metabolic syndrome
insulin resistance
skeletal muscle
electron transfer