Skeletal muscle dissemination in a dog with T-cell lymphoma.
Tommaso MagniFrancesca Del SignoreMassimo VignoliRossella TerragniAlessandro PoliFrancesca ParisiMichele SampaoloAndrea BoariArianna MiglioPaolo Emidio CrisiPublished in: Veterinary medicine and science (2022)
A 5-year-old spayed female American Staffordshire was referred for weakness, reluctance to move and distension of the abdomen. Three weeks before, the dog underwent surgery for excision of a nodular mass suspected to be a non-epitheliotropic cutaneous T-cell lymphoma (NE-CTCL). Computed tomography revealed heterogeneous enhancing mesenteric masses and nodular lesions of soft tissue density, and infiltration of the abdominal muscular wall. Moreover, a pattern of diffuse muscle nodules in the skeletal muscles was visible, with lesions showing homogenous, heterogeneous or ring enhancement. Necrosis was histologically observed and these lesions were infiltrated by CD3-positive and CD20-, CD79a- and Iba1-negative neoplastic lymphocytes. On the basis of the immunopathological features metastatic NE-CTCL was suspected. Skeletal muscle metastasis has been rarely reported in small animals and this case report further confirms that this possibility should be considered in dogs with lymphoma.
Keyphrases
- skeletal muscle
- computed tomography
- case report
- insulin resistance
- soft tissue
- pulmonary embolism
- minimally invasive
- small cell lung cancer
- squamous cell carcinoma
- diffuse large b cell lymphoma
- positron emission tomography
- magnetic resonance imaging
- single cell
- low grade
- atrial fibrillation
- dual energy
- pet ct
- contrast enhanced ultrasound