CUL4B facilitates HBV replication by promoting HBx stabilization.

Haixia ShanBo WangXiaodong ZhangHui SongXi LiYongxin ZouBaichun JiangHuili HuHao DouChangshun ShaoLifen GaoChunhong MaXiaoyun Yang Xiaohong Liang Yaoqin Gong

Published in: Cancer biology & medicine (2021)

CUL4B enhances HBV replication by interacting with HBx and disrupting its ubiquitin-dependent proteasomal degradation. CUL4B may therefore be a potential target for anti-HBV therapy.

Keyphrases

hepatitis b virus
liver failure
small molecule
stem cells
mesenchymal stem cells
human health