Endovascular Cooling Catheter for Selective Brain Hypothermia: An Animal Feasibility Study of Cooling Performance.

Giorgio Cattaneo M Schumacher Christoph Johannes Maurer J Wolfertz T Jost M Büchert A Keuler L Boos Mukesch Johannes Shah K Foerster W-D Niesen Gabriele Ihorst Horst Urbach Stephan Meckel

Published in: AJNR. American journal of neuroradiology (2015)

Sheep proved a feasible animal model for the intracarotid cooling catheter. Fast induction of selective mild hypothermia was achieved within the cooled cerebral hemisphere, with stable temperature gradients in the contralateral brain and systemic blood. Further studies are required to demonstrate any therapeutic benefit of selective cerebral cooling in a stroke model.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
brain injury
cardiac arrest
white matter
resting state
atrial fibrillation
multiple sclerosis
case control
aortic dissection