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Glycosylated 4-methylumbelliferone as a targeted therapy for hepatocellular carcinoma.

Gisela WeizMaria I MolejonMariana MalviciniCaecilia H C SukowatiClaudio TiribelliGuillermo MazzoliniJavier D Breccia
Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Our results provide evidence that 4MUR may be used as an effective HCC therapy, without damaging non-tumoural cells or other organs, most probably due to the specific targeting.
Keyphrases
  • induced apoptosis
  • cell cycle arrest
  • endoplasmic reticulum stress
  • cancer therapy
  • stem cells
  • signaling pathway
  • drug delivery
  • bone marrow
  • pi k akt
  • smoking cessation