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Altered multimodal magnetic resonance parameters of basal nucleus of Meynert in Alzheimer's disease.

Weimin ZhengHui LiBin CuiPeipeng LiangYe WuXu HanChiang-Shan R LiKuncheng LiZhiqun Wang
Published in: Annals of clinical and translational neurology (2020)
By combining multimode MR imaging, we demonstrated volumetric atrophy, hyperperfusion, and disconnection of the BNM in AD. These findings support cholinergic dysfunction as an etiological marker of AD and related dementia.
Keyphrases
  • magnetic resonance
  • contrast enhanced
  • mild cognitive impairment
  • cognitive decline
  • cognitive impairment
  • oxidative stress
  • pain management
  • magnetic resonance imaging