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ChIP-BIT2: a software tool to detect weak binding events using a Bayesian integration approach.

Xi ChenXu ShiAndrew F NeuwaldLeena Hilakivi-ClarkeRobert ClarkeJianhua Xuan
Published in: BMC bioinformatics (2021)
ChIP-BIT2 is an efficient ChIP-seq peak caller. It provides a better lens to examine weak binding sites and can refine or extend the existing binding site collection, providing additional regulatory regions for decoding the mechanism of gene expression regulation.
Keyphrases
  • gene expression
  • high throughput
  • circulating tumor cells
  • single cell
  • dna methylation
  • genome wide
  • rna seq
  • binding protein