Universal chromosomal microarray analysis reveals high proportion of copy-number variants in low-risk pregnancies.

Shira SternN HacohenV MeinerSimcha YagelS ZenvirtS Shkedi-RafidM MacarovD V ValskyShay PoratN YanaiA FrumkinHagit Daum

Published in: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (2021)

Although the background risk of identifying a clinically significant early-onset abnormal CMA result in pregnancies with a low a-priori risk is lower than that observed in high-risk pregnancies, the risk is substantial and should be conveyed to all pregnant women. © 2020 International Society of Ultrasound in Obstetrics and Gynecology.

Keyphrases

copy number
early onset
mitochondrial dna
pregnant women
preterm birth
pregnancy outcomes
genome wide
gestational age
late onset
dna methylation
magnetic resonance imaging
gene expression
contrast enhanced ultrasound