B cell response after SARS-CoV-2 mRNA vaccination in people living with HIV.

Jacopo PolvereMassimiliano FabbianiGabiria PastoreIlaria RancanBarbara RossettiMiriam DuranteSara ZirpoliEnrico MorelliElena PettiniSimone Lucchesi Fabio FiorinoMario TumbarelloAnnalisa CiabattiniFrancesca Montagnani Donata Medaglini

Published in: Communications medicine (2023)

The mRNA vaccination against SARS-CoV-2 elicits humoral and B cell responses quantitatively similar between PLWHIV and HCs, but there are important differences in terms of antibody functionality and phenotypes of memory B cells, reinforcing the notion that tailored vaccination policies should be considered for these patients.

Keyphrases

sars cov
end stage renal disease
respiratory syndrome coronavirus
ejection fraction
newly diagnosed
immune response
public health
chronic kidney disease
peritoneal dialysis
prognostic factors
smoking cessation