Mechanical stimulation-induced purinome priming fosters osteogenic differentiation and osteointegration of mesenchymal stem cells from the bone marrow of post-menopausal women.
Catarina Bessa-AndrêsRui Pinto-CardosoKaryna TarasovaAna Luísa Pereira-GonçalvesJoana Maria Gaio-Ferreira-CastroLiliana S CarvalhoMaria Adelina CostaFátima FerreirinhaAna Canadas-SousaJosé MarinhasRolando FreitasRui LemosAdélio VilaçaAntónio OliveiraSteven N EbertJosé Bernardo Noronha-MatosPublished in: Stem cell research & therapy (2024)
Data suggest that in vitro MS restores the purinergic cell-to-cell communication fostering the osteogenic differentiation and osteointegration of BM-MSCs from Pm women, a strategy that may be used in bone regeneration and repair tactics.