Tregs dysfunction aggravates postoperative cognitive impairment in aged mice.

Yile ZhouHuihui JuYan HuTingting LiZhouyi ChenYuan SiXia SunYi ShiHao Fang

Published in: Journal of neuroinflammation (2023)

Blocking peripheral regulatory T cells improves surgery-induced cognitive function in aged mice. Therefore, aged Tregs play an essential role in the occurrence of POCD.

Keyphrases

regulatory t cells
cognitive impairment
high fat diet induced
dendritic cells
minimally invasive
risk assessment
patients undergoing
oxidative stress
diabetic rats
coronary artery bypass
insulin resistance
adipose tissue
metabolic syndrome
acute coronary syndrome
surgical site infection