Pharmacokinetics of metronomic temozolomide in cerebrospinal fluid of children with malignant central nervous system tumors.
Sören BüskerWalter JägerStefan PoschnerLisa MayrValentin Al JalaliJohannes GojoAmedeo A AziziSami UllahMuhammad BilalLobna El TabeiUwe FuhrAndreas PeyrlPublished in: Cancer chemotherapy and pharmacology (2022)
Metronomic oral temozolomide penetrates into the CSF in pediatric patients, with even higher concentration levels compared to adults.