Quantification of Antifibrillarin (anti-U3 RNP) Antibodies: A New Insight for Patients with Systemic Sclerosis.

Audrey BenyamineDaniel BertinNoémie Resseguier Xavier Heim Julien BermudezDavid LaunaySylvain DubucquoiAdrian HijDominique FargeAlain LescoatIsabelle Bahon-RiedingerNouria BenmostefaLuc MouthonJean-Robert HarléGilles KaplanskiPascal RossiNathalie BardinBrigitte Granel

Published in: Diagnostics (Basel, Switzerland) (2021)

We demonstrate the usefulness of quantifying AFAs in the immunological exploration of SSc, especially when patients are seronegative for SSc conventional autoantibodies and display a typical IIF pattern. AFAs might constitute an interesting marker of SSc severity.

Keyphrases

systemic sclerosis
interstitial lung disease
end stage renal disease
newly diagnosed
ejection fraction
prognostic factors
rheumatoid arthritis
patient reported outcomes