Periplocoside P affects synaptic transmission at the neuromuscular junction and reduces synaptic excitability in Drosophila melanogaster by inhibiting V-ATPase.
Jiaojiao LuoAnqi SunYang YuYakun PeiYayun ZuoZhao-Nong HuPublished in: Pest management science (2023)
Our findings confirm that PSP can influence synaptic transmission at the neuromuscular junction of Drosophila larvae by targeting V-ATPase. These results provide a basis for investigating the mechanism of action of PSP and its potential application in designing novel insecticides. This article is protected by copyright. All rights reserved.