ANO7 African-ancestral genomic diversity and advanced prostate cancer.

Jue Jiang Pamela Xing Yi SohShingai B A MutambirwaM S Riana BornmanChristopher A HaimanVanessa M Hayes Weerachai Jaratlerdseri

Published in: Prostate cancer and prostatic diseases (2023)

Here we provide not only validation for ANO7 as an African-relevant protein-altering PCa-risk locus, but additional evidence for a role of inherited and acquired ANO7 variance in the observed phenotypic heterogeneity and African-ancestral health disparity.

Keyphrases

prostate cancer
healthcare
public health
radical prostatectomy
mental health
single cell
gene expression
health information
social media
small molecule
amino acid
climate change
genome wide