TRPV1 and TRPM8 antagonists reduce cystitis-induced bladder hypersensitivity via inhibition of different sensitised classes of bladder afferents in guinea pigs.
Stewart RamsayLauren KeightleySimon BrookesVladimir P ZagorodnyukPublished in: British journal of pharmacology (2022)
The data demonstrate the therapeutic promises of combination of TRPV1 and TRPM8 antagonists for the treatment of bladder hypersensitivity in cystitis.