Stereotactic Body Radiotherapy for Oligoprogression in Castration-Resistant Prostate Cancer: Early Toxicity Analysis of the TRAP Trial.

P H PatelS DreibeA ReidC ParkerJ MurrayA PathmanathanA TironaJ GuevaraY-E SuhJ FrewN PalaniappanI SyndikusG AttardN TunariuA C Tree

Published in: Clinical oncology (Royal College of Radiologists (Great Britain)) (2024)

In this prospective phase II clinical trial for OPD whilst on ARTA in the CRPC setting, we report low grade ≥ 3 toxicity after SBRT. There is no discernible change in patient-reported quality of life due to SBRT treatment. The final results of progression-free survival and toxicity of SBRT treatment will be reported once further follow-up is complete.

Keyphrases

phase ii
clinical trial
low grade
radiation therapy
free survival
patient reported
open label
phase iii
oxidative stress
high grade
study protocol
early stage
radiation induced
oxide nanoparticles