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Parkinson's Disease, NOTCH3 Genetic Variants, and White Matter Hyperintensities.

Joel RamirezAllison Ann DilliottMalcolm A BinnsDavid P BreenEmily C EvansDerek BeatonPaula M McLaughlinDonna KwanMelissa F HolmesMiracle OzzoudeChristopher J M ScottStephen C StrotherSean SymonsRichard H SwartzDavid GrimesMandar JogMario MasellisSandra E BlackAnne JoutelConnie MarrasEkaterina RogaevaRobert A HegeleAnthony E Langnull null
Published in: Movement disorders : official journal of the Movement Disorder Society (2020)
The NOTCH3 rare variants in PD may significantly contribute to increased WMH burden, which in turn may negatively influence cognition. © 2020 International Parkinson and Movement Disorder Society.
Keyphrases
  • white matter
  • multiple sclerosis
  • cell proliferation
  • copy number
  • fluorescent probe
  • sensitive detection
  • living cells
  • mild cognitive impairment
  • gene expression
  • dna methylation