The Influence of Body Mass Index on Growth Factor Composition in the Platelet-Rich Plasma in Patients with Knee Osteoarthritis.
Michał WicińskiDawid SzwedowskiŁukasz WróbelSławomir JekaJan ZabrzyńskiPublished in: International journal of environmental research and public health (2022)
BMI does not influence the level of selected growth factors in patients with knee osteoarthritis. Obese and non-obese patients had similar compositions of PDGF, TGF-β, EGF, FGF-2, IGF-1, and VEGF. PRP can be used in both groups with similar effects associated with growth factors' influence on articular cartilage.
Keyphrases
- knee osteoarthritis
- growth factor
- obese patients
- platelet rich plasma
- body mass index
- bariatric surgery
- gastric bypass
- roux en y gastric bypass
- weight loss
- type diabetes
- adipose tissue
- physical activity
- metabolic syndrome
- transforming growth factor
- vascular endothelial growth factor
- signaling pathway
- binding protein
- vascular smooth muscle cells
- angiotensin ii