Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression.

Brandon TarakuJoana R LoureiroAshish K SahibArtemis Zavaliangos-PetropuluNoor Al-SharifAmber M LeaverBenjamin S C WadeShantanu JoshiRoger P WoodsRandall EspinozaKatherine L Narr

Published in: Brain and behavior (2024)

Subanesthetic ketamine modulates functional pathways linking the Hb and NAc with visual, parietal, and cerebellar regions in MDD. Overlapping effects between Hb and NAc functional systems were associated with ketamine's therapeutic response.

Keyphrases

functional connectivity
resting state
pain management
transcription factor
major depressive disorder
working memory
genome wide analysis