Endoglin, a novel biomarker and therapeutical target to prevent malignant peripheral nerve sheath tumor growth and metastasis.

Teresa González Muñoz Angela Di Giannatale Susana Garcia-Silva Vanesa Santos Sara Sanchez-Redondo Claudia Savini Osvaldo Graña-Castro Carmen Blanco-Aparicio Suzanne Fischer Olivier De Wever Edgar Creus-Bachiller Sara Ortega-Bertran David J Pisapia José Luis Rodríguez-Peralto Juana Fernández-Rodríguez Cleofe Romagosa Rita Alaggio Maria Serena Benassi Laura Pazzaglia Katia Scotlandi Nancy Ratner Kaleb Yohay Charles P Theuer Hector Peinado

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Our data unveil a tumor-promoting function of ENG in MPNSTs and support the use of this protein as a novel biomarker and a promising therapeutic target for this disease.

Keyphrases

peripheral nerve
electronic health record
big data
amino acid
binding protein
artificial intelligence
deep learning