Loss of CELF2 promotes skin tumorigenesis and increases drug resistance.

Bindeshwar SahJasvinder SinghYao ShenNoah GoldfarbFaramarz H SamieLarisa J GeskinLiang Liu

Published in: International journal of dermatology (2024)

This study shows for the first time that CELF2 loss occurs during skin tumorigenesis and increases drug resistance in SCC cells, highlighting the possibility of targeting CELF2-regulated pathways in skin cancer prevention and therapies.

Keyphrases

skin cancer
induced apoptosis
soft tissue
wound healing
cell cycle arrest
transcription factor
cancer therapy