Case report of the first Caucasian burn patient transplanted with Cutimed Sorbact®-based cultured epithelial autografts technique at Tygerberg Hospital, Cape Town, South Africa: An 8-year follow-up.
Wayne George KleintjesTarryn Kay PrinslooPublished in: SAGE open medical case reports (2024)
Cultured epithelial autograft applications are limited by the associated cost and time constraints in resource-limited settings. A modified composite technique using the patients' own tissue and Cutimed Sorbact dressing was employed as a life-saving emergency measure. Since the non-Caucasian population was more commonly treated at the center, it was important to report the first Caucasian patient outcome, as the graft-take outcome for all populations was unknown. A 54-year-old male with extensive flame burns and a low chance of survival was admitted to the Tygerberg Burn Center. He received traditional skin grafts and cultured epithelial cells, after the 2 week-culture period using the current technique. Short- (⩽2 weeks) and long-term graft take (⩽8 years) was inspected. Good graft take and complete epithelialization was observed during short-term inspection with partially healed areas initially attributed to extensive burn depth and dressing removal. Long-term follow-up indicated a near normal tissue appearance and excellent pliability.
Keyphrases
- south africa
- case report
- wound healing
- endothelial cells
- newly diagnosed
- end stage renal disease
- african american
- hiv positive
- healthcare
- ejection fraction
- public health
- chronic kidney disease
- emergency department
- prognostic factors
- peritoneal dialysis
- clinical trial
- patient reported outcomes
- anterior cruciate ligament reconstruction
- adverse drug
- genetic diversity