Improved metal allergen reactivity of artificial skin models by integration of Toll-like receptor 4-positive cells.
Verena G FringsDamaris MüllerGabriel StorzAngela RossiHelga SennefelderChristian AdamMatthias GoebelerFlorian K Groeber-BeckerMarc SchmidtPublished in: Contact dermatitis (2019)
Our data suggest that FTSE or DC/RhE co-culture models can circumvent the shortcomings of RhE assays, and combine the benefits of complex and monoculture-based test systems in a single assay.