Maternal diet quality is associated with placental proteins in the placental insulin/ growth factor, environmental stress, inflammation, and mTOR signaling pathways: The Healthy Start ECHO Cohort.
Ellen C FrancisDana M DabeleaKristen E BoyleThomas JanssonWei PerngPublished in: The Journal of nutrition (2021)
Higher quality diet had sex-specific associations with placental protein abundance/phosphorylation. Given that these proteins have been correlated with neonatal anthropometry, our findings provide insight into modifiable factors and placental pathways that should be examined in future studies as a potential links between maternal diet and offspring metabolic health.Study registration ID: NCT02273297Study registration URL: https://clinicaltrials.gov/ct2/show/NCT02273297?term = NCT02273297&draw = 2&rank = 1.
Keyphrases
- growth factor
- physical activity
- weight loss
- type diabetes
- signaling pathway
- healthcare
- oxidative stress
- public health
- computed tomography
- mental health
- human health
- magnetic resonance
- preterm infants
- metabolic syndrome
- contrast enhanced
- magnetic resonance imaging
- climate change
- high fat diet
- small molecule
- quality improvement
- microbial community
- glycemic control
- pregnancy outcomes
- insulin resistance
- social media
- binding protein
- protein protein
- protein kinase
- positron emission tomography
- case control
- diffusion weighted