Glibenclamide pretreatment attenuates early hematoma expansion of warfarin-associated intracerebral hemorrhage in rats by alleviating perihematomal blood-brain barrier dysfunction.
Zongwei ZengLiang LiangZhou FengPeiwen GuoXiaoke HaoJishu XianHua FengYu-Jie ChenZhi ChenPublished in: Chinese neurosurgical journal (2023)
The results indicate that glibenclamide pretreatment in stroke primary and secondary prevention might be a promising therapy for hematoma expansion at the early stage of W-ICH.