Long-term outcomes of progestin plus metformin as a fertility-sparing treatment for atypical endometrial hyperplasia and endometrial cancer patients.
Akira MitsuhashiYuji HabuTatsuya KobayashiYoshimasa KawaraiHiroshi IshikawaHirokazu UsuiMakio ShozuPublished in: Journal of gynecologic oncology (2020)
MPA plus metformin is efficacious in terms of RFS and post treatment conception. Moreover, metformin may be more efficacious for patients with BMI ≥25 kg/m².