Convenient Preparation and Spectroscopic Characterization of 7R-Hydroxymatairesinol.
Eleonora ColomboGiuseppe PaladinoUmberto CirielloDaniele PassarellaPublished in: Molecules (Basel, Switzerland) (2021)
The preparation of 7R-HMR (allo-hydroxymatairesinol) is reported by: (a) NaBH4 kinetic reduction of 7R/7S diastereomeric mixture; and (b) epimerization of the C7 hydroxyl group by Mitsunobu reaction and subsequent ester hydrolysis. The availability of highly pure target compound (7R-HMR) made it possible to confirm the structure of the target compound and to complete the full spectroscopic characterization.
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