Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures.

María ArechederraMaría RullánIrene AmatDaniel OyonLucia ZabalzaMaria ElizaldeM Ujue LatasaMaria R MercadoDavid Ruiz-ClavijoCristina SaldañaIgnacio Fernández-UriénJuan CarrascosaVanesa JusuéDavid Guerrero-SetasCruz ZazpeIranzu González-BorjaBruno SangroJose M HerranzAna PurroyIsabel GilLeonard J NelsonJuan J VilaMarcin KrawczykKrzysztof ZieniewiczWaldemar PatkowskiPiotr MilkiewiczFrancisco Javier CuberoGorka Alkorta-AranburuMaite G Fernandez-BarrenaJesus M UrmanCarmen Berasain Matias A Avila

Published in: Gut (2021)

Implementation of Bilemut at the initial diagnostic stage for biliary strictures can significantly improve detection of malignancy, reduce delays in the clinical management of patients and assist in selecting patients for targeted therapies.

Keyphrases

end stage renal disease
newly diagnosed
chronic kidney disease
healthcare
primary care
prognostic factors
dna methylation
copy number
circulating tumor
loop mediated isothermal amplification