Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis.

Fabian FinkelmeierÖzge CanliKai-Henrik PeifferDirk WalterAndrea TalChristine KochUrsula PessionJohannes VermehrenJörg TrojanStefan ZeuzemAlbrecht PiiperFlorian R GretenGeorgios GrammatikosOliver Waidmann

Published in: PloS one (2018)

We conclude that a high CA9 level is a possible prognostic indicator for a poor outcome in HCC patients. The high CA9 levels are probably mainly associated with portal hypertension. Ductular reactions might be a possible source of serum CA9.

Keyphrases

protein kinase
newly diagnosed
ejection fraction
prognostic factors
endothelial cells
chronic kidney disease